Adjuvants In Vaccines - 1587 Words

The viruses that cause tumorigenic transformation produce oncoviral antigens. These antigens are recognized by the immune system as â€Å"non-self† because they are present on infected cells (Saxena and Bhardwaj 2017). Neoantigens, which are MHC restricted antigens, are produced by mutations in tumor cells so they are not found on all tumors. Because neoantigens are unique to the individual, vaccines that target these antigens need to be personalized (Saxena and Bhardwaj 2017). Finally, antigens that are over expressed significantly in tumor cells compared to normal cells are simply known as overexpressed antigens (Saxena and Bhardwaj 2017). Adjuvants in Vaccines Adjuvants are substances that can boost the immune system. They are extremely†¦show more content†¦Some New Adjuvants Nanoparticles are a recently developed type of adjuvant that help vaccines access the lymph nodes. These nanoparticles can allow the vaccine to be directly deposited into the lymph node, activating DCs and CTLs via intranodal injections. Nanoparticle vaccines may also reach the lymph node by lymphatic drainage. In the lymph node, CD8 CTLs are produced by cross-presentation of lymph node DCs (Saxena and Bhardwaj 2017). Nanoparticle vaccines could be vital for the future of cancer treatment. Another new type of adjuvants are self-polymerizing scaffolds. They incorporate TLR agonists and peptide antigens. This allows the molecule to remain water soluble at room temperature unlike TLR agonists. The scaffolds undergo temperature-dependent self-polymerization which makes immunogenic particles water soluble. These particles are drained to the lymph node where they activate DCs (Saxena and Bhardwaj 2017). Albumin binding agonists are effective because of the abundance of albumin in the blood and lymph. Vaccines with albumin binding agonists have TAAs with lipid tails that have a high affinity for albumin. Once bound, the vaccine is taken to lymph nodes. This vaccine type is known to safely advance CD8 CTL activation (Saxena and Bhardwaj 2017). Oncolytic viruses can also be used as vaccine adjuvants in oncolytic virus therapy, also known as virotherapy. This canShow MoreRelated##syl Lipid A ( GLA ) Adjuvants : Associated Antigen Portrayed In Fig1857 Words   |  4 Pagesprotective immunity that is required for an effective TB vaccine [12]. However, as is generally known, recombinant proteins are by themselves poorly immunogenic and need an adjuvant to stimulate adaptive immune responses. The Glucopyranosyl Lipid A (GLA) adjuvant is a synthetic Toll-like Receptor (TLR) 4 that is formulated as either a stable emulsion (GLA-SE) [13] or as a liposomal formulation containing QS21 saponin (GLA-LSQ). The adjuvants have been efficiently combined with the antigen for theRead MoreThe Search for an Alternative to Aluminium Based Vaccines1118 Words   |  4 PagesReported incidences of toxicity due to aluminium based vaccines have always been a concern (Clements, 1996; Clements and Griffiths, 2002; Edleman, 1997). Therefore, ther e has always been a constant effort to search for alternative adjuvants. Polymeric micro and nanoparticles can act as a delivery vehicle and along with their adjuvanting capabilities may enhance the efficacy of the vaccine (Gregory et al., 2013; Koping-Hoggard et al., 2005; Panyam and Labhasetwar, 2003). Biodegradable polymeric nanoparticlesRead MoreComparison Between Protective Antibody Response And Guinea Pigs Immunized With Wild Type ( Wt )1617 Words   |  7 PagesComparison of protective Antibody response in guinea pigs immunized with Wild type (Wt) BoHV-1 and ΔgE BoHV-1 mutant virus vaccine L.R.ANANTHAKRISHNA1*, MOHINI SAINI2, PRAVEEN K GUPTA3 and RIZWANA TABASSUM4 1Asst.Professor, 2, 3 Principal Scientist, 3Research Associate 1Department of Veterinary Physiology and Biochemistry; Karnataka Veterinary, Animal Fisheries Sciences University; Veterinary College, Vinobanagar, Shimoga- 577 204, India, 2Division of Biochemistry, 3 4Division of VeterinaryRead MoreSynthetic Muc1 Based Anticancer Vaccines1428 Words   |  6 PagesMore recently in 2011, Li and coworkers reported fully synthetic MUC1-based anticancer vaccines containing mono-, di- and tetravalent B-cell epitopes conjugated to TLR2 ligand (Figure 1.11).157 The B-cell epitope, MUC1 glycopeptide (HGVTSAPDT*RPAPGS*TAPPA) containing Tn and/or T antigen and TLR2 ligand, Pam3CysSK4 were prepared by solid-phase synthesis. Conjugation of MUC1 glycopeptide epitope and multivalent alkyne-functionalized lipopeptide (TLR2 ligand) was performed by using Cu+ catalyzed clickRead MoreRoutes Of Immunization And Effects Of Antigen Dose1248 Words   |  5 PagesThere are several standard methods of immunization and administering a vaccine via the correct route is a critical factor to the success of the immunization. Typically, vaccines are given intramuscularly, subcutaneously, by intradermal injection (the topmost layer of skin), orally, or intranasal via nasal spray. Vaccines containing adjuvants are usually given intramuscularly to help reduce adverse, local effects. Flu vaccines are often administered through a nose spray into the nasal passage. RecentRead MoreForgoing Vaccinations to Prevent Autism 1378 Words   |  6 Pagesafter famous celebrity Jenny McCarthy linked autism with measles-mumps-rubella (MMR) vaccination. Celebrity Jenny McCarthy stated that after her son got his shot of measles-mumps-rubella(MMR) vaccine, â€Å"Boom! Soul, gone from his eyes.(Bruni)† Her son was later diagnosed with autism in 2005. The vaccine given to the children contained live but sufficiently weakened or attenuated viruses to stimulate immune response. The capacity to stimulate immune response was from the ability of human immuneRead MoreThe Importance Of Vircines1108 Words   |  5 Pages2.3.3. Gene deleted vaccines The knowledge of specific virulence factor(s) of a pathogen and the availability of recombinant DNA technology has facilitated the creation of specific gene-deleted pathogens for use as live vaccines. The approach of creating and testing defined gene deletions ultimately aids in reducing the pathogenicity/virulence of the organism without affecting the immunogenicity. Such gene-deleted organisms can be used as vaccines as they retain the immunogenic features of the wild-typeRead MoreExplain The Mechanism Of RIG-I Recognizes Bacterial Ligands In Glial Cells?792 Words   |  4 Pagespathogens by glial cells is currently unknown. The experiments in this proposal will illustrate the contribution and the mechanism of RIG-I mediated bacterial recognition to antibacterial glial cell responses. RIG-I agonists have potential use as vaccine adjuvants. RIG-I recognition of double stranded RNA with a 5’ triphosphate group triggers an innate immune response characterized by cytokine, chemokine, and interferon production. RIG-I activation is important for the innate immune response to pathogensRead MoreAbstract: â€Å"Nanoparticle Vaccines†, An Article Written By1226 Words   |  5 PagesAbstract: â€Å"Nanoparticle vaccines†, an article written by Liang Zhao et al. condenses a large amount of information on the topic of nanovaccinology and presents that information in an organized and straightforward manner, however, it only scratches of the field and the lack of clarity relating to its audience can lead to it being confusing. The article could prove useful to a scientist possibly interested in doing research in nanovaccinology, however it would likely not be any new information forRead MoreA Brief Note On Lipid Based Delivery Systems1499 Words   |  6 P agesas have multichamber structure allow encapsulation and co-encapsulation of various therapeutics of different weight range with different solubilities. Biphasic systems are evaluated for many vaccine candidates including proteins, nucleotides, recombinant subunits and classical old inactivated or killed vaccines and now became applicable to purposes in human as well as in animals [150,148,149]. Baca-Estrada et al., [150] has shown topical delivery of hen egg lysozyme (HEL) and leukotoxin antigens in

Analysis Of Fresh Fruit, Broken Bodies By Seth Holmes

In the ethnographic text, Fresh Fruit, Broken Bodies, by Seth Holmes, Holmes describes his experience on enduring the living and working conditions of migrant workers. Seth Holmes’ social positions and identities helped bring the ethnography forward by showcasing the stories of Triqui migrant workers and how they suffer in everyday life because of the cycle of suffering. On the other hand, Holmes risks credibility and validity as the ethnographic text is taken from his point of view as a white man rather than a Triqui worker’s. As the author of the ethnographic text, Seth Holmes takes an in-depth look inside the lives of the Triqui workers and the problems they encounter in the face of racism and the social, political, and economic†¦show more content†¦As an anthropologist, Holmes discusses how the Triqui workers are structurally vulnerable in this way because of the structural, political, and economic factors forcing them to work under these conditions. As a white man, the contrast of how Holmes is treated compared to the Triqui workers shows the mistreatment Triqui people receive on a daily basis. When Holmes and his Triqui companions were at Burger King, they expected to receive an order with four large fries but instead, only received three medium fries, showing the mistreatment they received outside of a work setting. Holmes’ stated, â€Å"They explained to me that they could never do such a thing because they would not be given different fries and would likely get in trouble for asking. Samuel told me to go up to see what they would do {....} they gave us four large fries and apologized kindly-resentfully.† (37) Because of Seth Holmes’ race as a white man, he immediately notices that the cashier treated him fairly but treated the companions as if they were inferior and that they did not deserve to receive the respect that was given towards Holmes. From that point on, Holmes realized the the vast difference between his race and the amount of power he had versus the Triqui people who had no power to control situations like this. Because of the Triqui companions’ inferiority, they feel a sense of low confidence and fear to approach people that are higher on the economicShow MoreRelatedAnalysis Of The Book Fresh Fruit, Broken Bodies By Seth Holmes1841 Words   |  8 Pagesmigrants are forced to migrate to the United State in order to survive. They constantly risk their lives to cross a dangerous border in order to find the jobs that the American people don’t want to endure. In the book called â€Å"Fresh Fruit, Broken Bodies†, the author, Seth Holmes focuses on the lives of an indigenous Mexican group called the Triquis. Throughout the book, he focuses on the journey of the group from their hometown of Oaxaca to farms in California and Washington. The book also emphasizesRead MoreProject Mgmt296381 Words   |  1186 PagesCross Reference of Project Management Bod y of Knowledge (PMBOK) Concepts to Text Topics Chapter 1 Modern Project Management Chapter 8 Scheduling resources and cost 1.2 Project defined 1.3 Project management defined 1.4 Projects and programs (.2) 2.1 The project life cycle (.2.3) App. G.1 The project manager App. G.7 Political and social environments F.1 Integration of project management processes [3.1] 6.5.2 Setting a schedule baseline [8.1.4] 6.5.3.1 Setting a resource schedule 6.5.2.4 ResourceRead MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 Pageson Social Networking †¢ New section on Persuasive Communication strategies †¢ Discussion of how to frame messages for maximum impact †¢ Discussion of the effects of authority, expertise, and liking on communication effectiveness †¢ Updated discussion of body language in communication †¢ Introduces new ideas about the effects of electronic communications †¢ New Point–Counterpoint (Social Networking Is Good Business) †¢ New An Ethical Choice (The Ethics of Gossip at Work ) †¢ New Case Incident (Using Social Media

Long Journeys Begin With Baby Steps Essay free essay sample

, Research Paper The twenty-fifth day of remembrance of the Supreme Court determination that created a # 8220 ; constitutional right # 8221 ; to abortion is January 22, 1998.Even though abortions have been performed for many old ages, this controversial issue is still being debated among legion people. The competition between pro-choice and pro-life advocators has caused a great quandary in the United States. Many Americans have protested Bill Clinton because in 1993, he issued a series of executive orders and veto menaces which overturned a figure of pro-life policies. However, while these enormous arguments go on legion guiltless lives are being lost at the custodies of abortion. Abortion is any process for ending a gestation. In the instance Roe vs. Wade the tribunal allowed provinces to curtail abortions to the 3rd trimester, except where it is necessary for the saving of life or wellness of the female parent. However, in Doe V. Bolton the comrade instance to Roe vs. Wade the tribunal defined # 8220 ; wellness # 8221 ; to include all factors relevant to the wellbeing of the patient. Because of this wide definition of # 8220 ; wellness # 8221 ; the tribunal permits abortions right up until birth for about any ground. This is incorrect because by hebdomad 12 of the gestation all organic structure variety meats of the foetus are working. If the bosom is pumping blood throughout the organic structure, the babe is alive. I feel that killing any living being is slaying. There are assorted abortion techniques, but the most common is suction-aspiration. The abortionist inserts a hollow plastic tubing into the dialated womb. This tubing is attached to a suction machine, and when the machine is turned on the womb is emptied by suction. The suction tears the babe # 8217 ; s organic structure as it is being pulled through the hosiery. Because the process is so intense it causes great emotional and physical hurting for the female parent. There are legion physical hazards of abortion. During the process the patient can see intense hurting, harm to other variety meats, or in terrible instances decease. But, physical hazards continue after the clinic stopping points. Some have inordinate hemorrhage and infection that can do daze. Others may even hold parts of the babe left indoors. These hazards continue on for old ages. The adult female may hold jobs acquiring pregnant once more and if she does there is a higher hazard for tubal gestations, abortion, and premature births. However, for the bulk of abortion patients the physical lesion heals, but an emotional cicatrix remains. Beyond the physical hurting, the difficult world still exists that adult females suffer mental and emotional torment from abortion. Almost every adult female # 8211 ; whatever her age, background, or sexuality- has trauma at destructing a gestation. This is portion of a adult female # 8217 ; s ain life. If she destroys a gestation, sh vitamin E is destructing a portion of herself. Many recognize that they can non deny that something was physically being created inside them. This realisation and sorrow among legion adult females causes jobs in the deepest degree of her consciousness. They so feel that their ground for the abortion was non that of import. Reasons for abortion may change from gestation as a consequence of colza to a signifier of birth control. Some promiscuous adult females do non worry about birth control because they cognize that if they get pregnant abortion is easy available. If such an option was non offered it would coerce more adult females to utilize some signifier of birth control. However, victims of colza do non hold the option of birth control, therefore are frequently encouraged to hold an abortion. Rape is a really emotional subject, and people frequently feel that abortion is acceptable in these instances. However, the kids conceived through sexual assault besides hold a voice which needs to be heard. Every life regardless of how it was formed has value and a intent. It does non count how a kid begins, but who it will go. Pro-choice protagonists, nevertheless, have different sentiments. The chief statement of pro-choice people is the adult female # 8217 ; s right to take. But, how can anyone hold the right to take to kill another person? The lone existent pick in abortion is between a unrecorded babe and a dead babe. Many besides believe that if legal abortions are banned, adult females will fall back to endorse ally abortions. In 1972, the twelvemonth before the supreme tribunal legalized abortion, a sum of 39 adult females died from illegal abortions. However, the figure of maternal casualties go oning countrywide is in the high 100s. This figure does non include the legion babes losing their lives. Congress should make more to salvage the 1000000s of babes aborted each twelvemonth. The battle to stop abortion resembles the battle to stop bondage. The conflict against bondage was barbarous, and continued decennaries after the 13th, 14th, and 15th Ammendments became a portion of our Constitution. The conflict confronting the pro-life motion began long before the 1973 Roe vs. Wade determination and it may go on for old ages, but we show some marks of advancement after old ages of sorrow. And as you can see, I feel that the beginning of life is construct. Therefore, abortion during any portion of the gestation is the slaying of a kid, and every kid should hold a opportunity at life. If it is denied this opportunity we will neer know the joy and potency that these lost kids may hold provided the universe. Therefore, we must go on to work to alter the Black Marias and heads of the populace every bit good as those of the adult females in crisis gestations. Because if a foetus were non alive why would it turn? After all, long journeys begin with baby stairss.

Transcendentalism Essays (583 words) - Transcendentalism, Lecturers

Transcendentalism Transcendentalism is the belief that matters of ultimate reality transcend, or go beyond, human experience. Transcendentalist thinking began during the American Renaissance with writers like Ralph Waldo Emerson and Henry David Thoreau. However transcendental thinking did not begin with Thoreau and Emerson, but as Emerson called it, "it is the very oldest of thoughts cast into the mold of these new times." Transcendentalism is based on the ancient philosophy of Idealism, which originates with Plato, a well-known philosopher from ancient Greece. Transcendentalism is an appropriate way of thinking for the period known as the American Renaissance because it puts one into a state of mind that is more conducive to creative writing and thought. Transcendentalism is a lot to swallow, especially for many people of that time. Herman Melville totally captured the common man's reaction to the whole concept when he said, "what stuff all this is." It really takes a trained mind to grasp the concept of this spiritual world that Emerson describes. Many people do not believe in things that they cannot see, hear, touch, taste, or smell, so the extremely abstract concept of transcendentalism is totally out of their reach. However, for the people that can grasp this idea, it is very fulfilling. Transcendentalism makes people feel closer to God, in tune with nature, and gives a person a sense of self-worth. A major aspect of transcendental thinking is the individual defiance against the established orders of society. Henry David Thoreau conveys his feeling about this when he says; "That government is best which governs not at all." He believes that the ineptitude of the political leaders far out-weighs the amount of good that they could do. He also states that "They who have been bred in the school of politics fail now and always to face the facts." In this, he means that politicians ignore reality when it does not serve their purpose. This is true for modern times as all can see in the present political situation of the United States. Politicians are ignoring reality to serve their own personal and partisan agendas. The transcendentalists even went as far as to set up their own communities, the most famous of which, Brook Farm. Brook Farm, a self-governing, experimental community, lasted only six years, (the longest of all the transcendental communities), is where many famous authors of the American Renaissance call home for a part of their lives, and is even the setting for Nathaniel Hawthorne's Blithedale Romance. Hawthorne lived at the Farm for a little while, but left because he could not stand the highly intellectual and spiritual conversation. Brook Farm was a great outlet for these people to express their ideas and communicate with people who share those same beliefs without the fear of persecution by people that did not understand. The transcendentalist movement can and often is compared to another famous movement in American history, the"hippie" movement of the sixties. In many ways the "hippies'" movement paralleled the transcendentalists', and the "hippies" even form their own little communities, like Brook Farm, called communes. Both of these movements were important to help shape thinking, writing, and social ideals. The transcendentalist movement brings to the table an increased awareness of the world around oneself, with and a commitment to the spiritual aspects therein, and the "hippie" movement in the sixties gives Americans an increased awareness of their fellow man, with and emphasis on freedom and love. The transcendentalist movement has many good aspects to it that if applied today, could still teach everyone a few things about themselves and their lives. Plato, Emerson, Thoreau, and many others really did have a level of intelligence that transcended their contemporaries and the generations and generations after them.

Classic Christmas Carols for ESL Classes

Classic Christmas Carols for ESL Classes To use these Christmas Carols in English class, first, listen to a recording (or two) which you can easily find by searching on YouTube or other video sites with the title of the song. Print out the words, and follow along with the song. As you become more familiar with the words, start singing the along with the recording. Finally, sing the song as a class to bring in some Christmas spirit into the classroom. Another Christmas tradition is the reading of by Twas the Night Before Christmas by Clement C. Moore. Classic Christmas Songs Jingle BellsSilent NightJoy to the WorldThe First NoelWe Wish You a Merry ChristmasOh, Come All Ye FaithfulHark the Herald Angels SingWhat Child Is This?We Three KingsAuld Lang SyneAway in a MangerDeck The HallGod Rest You Merry, GentlemenHave Yourself a Merry Little ChristmasLo, How a Rose Eer BloomingO Christmas TreeRudolph the Red-Nosed ReindeerLullay Thou Little Tiny Child Singing Carols in Class: Suggestions for Teachers Find a good recording of the Christmas carol and play it for the class twice without any text. Just let the students listen and do their best to understand.Provided a printed version of the lyrics with gaps for keywords. Practice together as a class as a listening gap fill exercise.  As a class, brainstorm the words that are difficult to pronounce. Isolate the words and practice as minimal pairs with similar sounding words to help students understand differences in vowel sounds.  Choose a specific carol a few weeks before Christmas. Spend five or ten minutes in each class understanding, practicing and perfecting your carol. For larger classes, have students break up into smaller groups and learn different carols.If you are teaching young English learners, put on a small concert for the parents of children in your class. Choose three to five carols and perfect them as a class. After the last class before Christmas, put on a mini-concert for the parents.If your students are outgoin g, have a recital. Each student can choose a favorite carol and the class can sing for each other. Its fun, but a challenge!

Write a great resume even if you’ve never had a job

Write a great resume even if you’ve never had a job Looking for a job can feel like a catch-22: to get a job I need experience, but to get experience I need a job. And if you’re a student with no work experience or otherwise entering the workforce for the first time, how do you deal with that on a resume? You can’t just hand in a blank sheet with your name and address at the top. But don’t panic- you’ve got more than you think you do. Find experience in other places.You don’t have much full-time work experience yet, but you likely have experience in other areas. Have you volunteered? Are you a member of any clubs? Do you have any unpaid internships or other experience that’s close, but not quite, paid working experience? Any part-time jobs?Those may not be direct lines to the job for which you’re applying now, but you can talk about the skills and experiences you’ve had that have prepared you. Even hobbies may have a place here, as long as they’re relevant to the job you w ant- and, more importantly, appropriate. (Think â€Å"playing the violin† and not â€Å"crushing it on Xbox Live.†)For example: if you babysit on weekends, that shows responsibility. If you volunteer at the senior center sometimes, play up responsibilities and the skills you’ve learned and used there (like people skills or patient care skills). If you get to use your ninja math and organization skills as the treasurer of a club, definitely include that on your resume.Use academic experience.If you’re just starting out, whoever’s reading your resume likely understands that you’re light on experience. Academic courses and experience can come in handy here, especially if you’ve taken classes or become certified in the field where you’re trying to get a job. Don’t list every class you’ve ever taken, but a targeted list of relevant academic experience can help fill out your resume.Play up your skills.Here’s wher e you lean on personal qualities instead of personal experience. Bilingual? List it. Can do a vlookup like nobody’s business? That’s Excel expertise- list it.And if you’re feeling light on skills as well as experience, don’t sweat it. Skills are something you can build with time and effort, not just prior experience. You don’t need work experience to take a class on coding or public speaking. And those are skills that look great on a resume- ones you can highlight.Build your brand.It can be hard to develop a professional brand if you don’t yet have a job, but there are some things within your control here. If you’re interested in getting a job in graphic design, build a site where you can showcase your work. If you’re interested in social media, build up your presence and focus your energies on developing a professional network in the field in which you want to work.Bottom line: you have more experience than you think you do. W hen you’re building a resume without the luxury of having work experience, look at all aspects of your life for skills and bullet points that you can use to show you’re an awesome entry-level candidate.

Employment Law Research Paper Example | Topics and Well Written Essays - 2000 words

Employment Law - Research Paper Example Having independent contractors makes the business owners to avoid paying some accounting burdens such as overtime charges, workers compensations, health insurance costs, pension plans, and other employee benefits i.e. off duties, time rest periods like lunch breaks, and meals allowances. The business is also able to avoid such employees cost fulfilling business laws and regulations and the necessary charges. However, many workers may also decide to independent contractors in order to reduce expenses that employees face such as individual income tax return. Given all these benefits of classifying employees as independent contractors, what is the reason why employers would not treat his workers as independent employers? This is may be because of the consequences that may result if the Internal Revenue Service or even court finds out that a certain worker is an employee rather than independent contractor (Berson 50). If IRS gets an employer in such situation, the employer will pay full amounts for FICA portion, unemployment taxes, and compensation to the employee during the period in question. Additionally, all involved business directors and officers will be required to pay a penalty of 100% for the compensation of all withholding taxes, which are not paid. Following the recent introduction of the Employee Misclassification Prevention Law, and the preferred increment of $25 million dollars in 2014 federal budget for the labor department, employers can be sure of increased inspection by the government on classification of workers (Emerson 254). The Internal Revenue Services has also made announcement of inspecting over 6,000 businesses in the next three years in the firms, which are believed to have high rate of workers misclassification. Those employers who will be guilty will be forced to pay the set penalties. Although the mentioned industries by the Internal Revenue Service does not include, insurance, those employers found to use reasonable number of independ ent contractors will be a highly targeted. This will happen to be a great loss to such employers because of the penalties payments. In addition to such tax consequences due to worker misclassification as an independent contractor, if the law court was to make such determinations of whether a particular worker is not an independent contractor, the business owners will be subject to pay the claims that the worker could get. Such claims include; health allowances, retirement pension, and other employees’ fringe of benefits. The business will have to pay these benefits out of its own revenues. For instance, if such a worker was injured while working in business, the business will be liable to pay compensations to that particular worker and other benefits that the worker would have received from insurance if he had been a member of worker’s compensation insurance. The business may also be subject to suffering, pain, punitive, and pay penalties for failing to register its wo rkers with the worker’s compensation insurance coverage. Therefore, it is now easy to understand why an employer must be keen when making decisions on whether to classify a particular worker as employee or independent contractor. An error in classifying a certain worker as an independent contractor, instead of employee may be very expensive to both the business and the owner. Generally, business owners should use the â€Å"common law† definition of employment to determine whether to classi

Discussion Response Essay Example | Topics and Well Written Essays - 250 words - 1

Discussion Response - Essay Example Government machinery was deployed in both cases to ensure that the leaders’ ideologies were implemented. This took the form of mass violence, the establishment of concentration camps, and strict control of every aspect of the people’s lives as you rightly state. I have learnt from you one main difference between Hitler and Stalin that never was on my mind; the faà §ades they presented in public. I like the way you put it; Stalin’s speech and presentation in public light was positive while the actions he did or oversaw were quite the opposite, unlike Hitler who never minded what others thought of him. That said, I will like to add a point to your post in relation to the differences of the two regimes. While both regimes were oriented toward the good of the state as opposed to the individual, they were different in the sense that the Nazi movement focused on eliminating inferior races and people from the country while the Soviet regime was focused on eliminating class differences as noted by Kershaw and Moshà © (1997). In some sense, therefore, the two regimes used the same means (violence and strict controls) to meet different ends (establishing a pure Aryan state versus eliminating class

Beowulf Comparison Essay Example for Free

Beowulf Comparison Essay Beowulf is a very appealing novel as well as a film. The novel Beowulf and the film have many similarities, but they have more differences then anything. While watching the film I noticed many added parts that were not included in the novel. In the film, Grendel’s arm caught is caught on a rope as he’s trying to escape. As the men get closer he has no choice but to cut his own arm off in order to escape, this action is an actual animal reaction when their limb gets caught, the eat their own limb off. This event does not occur in the novel. In the novel Grendel is described as an evil monster with claws, while in the film he appears to be a regular human being. There is also some romance that goes on in the film. Another difference is that the novel is written in very old English while the English in the film seems a little more modern. Religion also seemed to play an important role in the film that it didn’t play on the novel. Before I watched the film I expected an ugly demon looking thing to play the role of Grendel, but instead he was just a very tall man with birth defects. In my opinion Grendel is not the monster the book makes him out to be. When Beowulf becomes furious with Grendel he begins to mimic Beowulf in amusement. While in the novel Grendel becomes angry and goes completely wild. I found both the novel and the movie amusing because they both had something different to offer. Reading the book allows you to visualize the characters and what their personality traits are going to be like. The novel will also allow me to better understand the climax and main points. As far as the film goes, it really helped me comprehend what is going on in the story, due to the novel being in Old English. After reading the novel I expected the film to be distinctively different, especially the way Grendel was portrayed. Despite the differences from the novel and the film, they both give me a clear understanding of what is occurring in the story.

Nietzsches Portraiture: Wagner as Worthy Opponent :: Wagner Nietzsche Philosophical Papers

Nietzsche's Portraiture: Wagner as Worthy Opponent ABSTRACT: Richard Wagner always represented for Nietzsche the Germany of that time. By examining Nietzsche's relationship to Wagner throughout his writings, one is also examining Nietzsche's relationship to his culture of birth. I focus on the writings from the late period in order to clarify Nietzsche's view of his own project regarding German culture. I show that Nietzsche created a portrait of Wagner in which the composer was a worthy opponent-someone with whom he disagreed but viewed as an equal. Wagner was such an opponent because he represented the disease of decadence which plagued the culture and from which Nietzsche suffered for a time, but of which he also cured himself. In other words, Nietzsche emphasized his overcoming and revaluation of Wagner because he wanted his readers to understand it as a metaphor for his larger battle with decadence in general. The goal of this portraiture is to demonstrate on an individual level what could be done on a cultural level to revitali ze culture. Through an analysis of Nietzsche's portrait of Wagner in the late period, I will claim that in order to understand Nietzsche's revaluation of decadent values in nineteenth century German culture, one must understand his relationship with the composer. From The Birth of Tragedy, where Wagner's music represented the hope for the re-birth of pre-Socratic Greek culture to The Case of Wagner, where Wagner was the artist of German decadence par excellence, Richard Wagner always personified nineteenth century Germany for Nietzsche. By examining Nietzsche's relationship to Wagner throughout his writings, one is also examining Nietzsche's relationship to his country of birth. In this paper, I carry out such an investigation with a focus on the late period (the writings after Thus Spoke Zarathustra) in order to clarify Nietzsche's view of his own project regarding German (and by extension European) culture. I show that in the late period Nietzsche created a portrait of Wagner in which the composer was a worthy opponent; meaning someone with whom Nietzsche disagreed but viewed as an equal. Nietzsche himself took on several worthy opponents, and he claimed that in his battle with "these objects of resistance" he learned about himself. Wagner was such an object of resistance because he represented the disease of decadence which plagued the culture and from which Nietzsche emphasized his overcoming. The goal of this portraiture was to demonstrate on an individual level what could be done on a cultural level to revitalize the culture and make it healthy.

Cognitive Aging Reflection Paper

Patrick Byrnes Dev. Psych 10/18/2012 Reflection on using it†¦or losing it In â€Å"what and When of Cognitive Aging† I immediately took issue with the fact that Salthouse used participants â€Å"recruited through newspaper advertisements, appeals to community groups†¦all with approximately 16 years of education†. I feel that this sampling would inherently create a sampling error. I feel that schooler was right in addressing the sub-groups of different types of work force variable plus time in work force.The participants in Salthouses study were anything but random, and never took into consideration the type of work (cognitive challenging or not) and amount of time in the workforce or whether still in the workforce. A group of doctors and professors might who worked well past legal retirement age might produce a much more varied result then say a group of business people, or factory workers. Although it should be noted that Schooler noted this in her paper and said that her finding were negative for impact of intellectual flexibility.I also take some issue with the coding for the â€Å"cigarette commercial† question posed by Schooler. While points were awarded for the person who could come up with both sides of an argument, and none for the person who could think of no reason, it does little to elaborate for the person who can only give one argument against the commercials seeing that would fit into today’s paradigm that cigarettes are a carcinogen and inherently bad for the user and nearby nonsmokers as well.Both papers it should be noted are based in cognitive psychology/theory. Relying heavily on scientific modeling and statistical evidence to use as evidence and draw conclusions from, in most all of the statistical models most of the data has been adjusted then sometime readjusted to accommodate multifactorial functions. Something one would not see with Freud, psychosocial studies, or classical conditioning, at least not to this degree and intricacy.Another idea that caught my attention was that the idea that some cognitive degradation will be camouflaged due to the fact that the aging adult modifies their behavior to overcome or avoid the growing deficiency. This would make it plausible for a type of â€Å"micro† black swan theory/event where surround family and friends did not see the ailing person’s disability until some calamitous event, only afterwards were all the signs actually seeable.

I Heart Huckabees: Concept of Dasein Essay

This is one of my attempts to highlight a few of the connections between the thought provoking scenes of this movie and the Existential movement in 19th and 20th century Philosophy. I do list and describe a few scenes and quotes, so i’ll throw on a SPOILER alert just in case. One of the most prominent concepts in I (Heart) Huckabees is that of Martin Heidegger’s Dasein. Dasein, literally meaning â€Å"Being-there†, is Heidegger’s method in which he applies another prominant Existential philospher, Edmund Husserl’s phenomenology to human beings themselves. What it does is instead of defining a â€Å"thing† and putting it into a preconceived category, one waits for the â€Å"thing† to reveal itself in its own time. The remarkable thing about Heidegger is that he never calls human beings â€Å"man†, but instead we are Dasein – in other words, we are simply in a field of being where we are free to define who we are for ourselves. Our being Dasein is our â€Å"thrownness† into life(a prominant theme to the Existential movement), and we are â€Å"thrown† into life with other Dasein(you and I). This then leads to mitdasein (â€Å"with-there-being†), meaning we are still â€Å"being-there†(Dasien), but now we are there with other Dasein. I (Heart) Huckabees demonstrates Heidegger’s Dasein and mitdasein multiple times, usually emphasized by Dustin Hoffman’s character, Bernard. In the first few scenes of the movie, Bernard speaks of infinity and â€Å"the blanket. † He holds up a blanket and asks us to imagine that it is the entire universe. Each part of the blanket is a different person, place, or thing; whether it is a hammer, or Paris, or you, the reader of this review. The point he makes is that everything in the universe is interconnected and we can’t tell where one person begins and another ends. Bernard also tells us, â€Å"The universe is an infinite sphere, the center is everywhere and the circumference is nowhere. † This is a wonderful example of Heidegger’s Dasein; our being has no outside to speak of, it is totality. The blanket represents mitdasein, demonstrating that we are not alone in our infinite field of being, but instead are accompanied by every other Dasein, all overlapping. Another of Heidegger’s Existential ideas is tossed about in I (Heart) Huckabees, though not as defined as the illusions to Dasein. When Tommy (Mark Wahlberg) and Albert (Jason Schwartzman), meet the French nihilist, Caterine (Isabelle Huppert), she introduces Heidegger’s concept of authenticity and inauthenticity. In the scene, Caterine has Tommy and Albert repeatedly bash each other in the face with a large ball; they continue to hit one another until the one being beaten ceases to think for a brief period. They have discovered what Caterine calls â€Å"Pure Being. † In ceasing to think, Albert and Tommy are allowed to simply be free to exist (Dasein, again), but they are soon pulled back in their minds, which Caterine names human drama. Though they think they can teach themselves to stay in a state of â€Å"Pure Being† all the time, Caterine explains that it will always be a cycle, going from â€Å"Pure Being† to human drama and back again. According to Heidegger, before we realize our selves, we are in a state of Verfallenheit, or â€Å"fallen-ness. † In this state, we are slaves to what Heidegger calls the One (â€Å"human drama†), or rather the public life. We are part of this public creature and we are categorized for being as such. This constricts us as Dasein and doesn’t allow us to realize our full potential. It is during this state of Verfallenheit, and being part of the One, that we are inauthentic. We are not being true to ourselves as Dasein, and therefore not allowing ourselves to rise to the level of existence we need to reach. It is only when we break free from the One and enter the level of Self that we become authentic, true selves. Heidegger understands, however, that sometimes we are pulled back into Verfallenheit, and must then go back through the One, or human drama as Caterine puts it, and back into the level of self. As Heidegger explains our cycle of inauthenticity and authenticity, Caterine explains much the same thing in her description of the cycle between â€Å"Pure Being† and human drama. Another I (Heart) Huckabees scene with high existential fiber is the short poem about a rock which Albert has written for his â€Å"open spaces† campaign: â€Å"Nobody sits like this rock sits. You rock, rock. The rock just sits and is. You show us how to just sit here†¦ and that’s what we need. † The poem brings to light the term Being-for-itself (etre pour soi), which is most closely associated with famous Existentialist Jean-Paul Sartre. Because of our consciousness, this term is most often applied to human beings and states that we are always beyond ourselves, thinking thoughts of ourselves, obsessively thinking of our pasts and futures, etc. This causes alot of pain and suffering for human kind – causing us to view ourselves in the future or judge ourselves according to the past – failing to be in the present moment, in the NOW. Unlike the rock which is always in the present moment, or, â€Å"being-in-itself†, Sartre believes that we can never possess ourselves fully. We can posses the rock, however, because it is a thing. The rock is not conscious, it is what it is at all moments†¦ but this is something impossible for humans because of our capability to go beyond ourselves in consciousness. In the final scene of the movie, Albert and Tommy are sitting on the rock and Albert claims that â€Å"The interconnection thing is definitely for real. † Heidegger would smile at Albert’s newfound discovery of mitdasein, that we are not alone in our infinite field of being, but instead are accompanied by all others. â€Å"Everything is the same, even if it’s different. † In this closing scene, in the same place as when the movie opened, seeing them both there on the rock made it hard not to think of the characters Vladimir and Estragon from Samuel Beckett’s Waiting for Godot, a famous Existential play in which two men wait endlessly in the middle of nowhere for a man named â€Å"Godot†. The Existentialism that gave birth to many of the scenes in the movie, I believe to be numerous. I have only touched upon a fraction of these. For example, two very famous philosophers – Friedrich Nietzsche and Soren Kierkegaard – can be seen as represented by the characters of Caterine and Bernard. Nietzsche, most well known for his claim that â€Å"God is dead†, may very well be an incarnation in the philosophy shown by Caterine. Kierkegaard on the other hand, who believed that God is not dead, but trully being faithful requires a â€Å"leap of faith†, is brought alive in the enlightening and â€Å"soft† teachings of Bernard and his wife. I wont go into further detail about the works of these two men, but encourage anyone interested to read deeper into their two philosophies†¦ you will certainly find more connections between the movie and the Existential movement. I hope this has helped share some light on those both perplexed by the movie and those interested in knowing the deeper historical and philosophical aspect of I (Heart) Huckabees. If you take some time to educate yourself on the background of Existentialism, you may find that I (Heart) Huckabees prooves to be a totally different experience when viewed a second time around.

Stroke Warning Signs Seen Hours or Days Before Attack

Stroke Warning Signs Seen Hours or Days Before Attack Warning signs of a stroke may appear as early as seven days before an attack and require urgent treatment to prevent serious damage to the brain, according to a study of stroke patients published in the March 8, 2005 issue of Neurology, the scientific journal of the American Academy of Neurology. A total of 80 percent of strokes are ischemic, caused by the narrowing of the large or small arteries of the brain, or by clots that block blood flow to the brain. They are often preceded by a transient ischemic attack (TIA), a â€Å"warning stroke† or â€Å"mini-stroke† that shows symptoms similar to a stroke, typically lasts less than five minutes and does not injure the brain. The study examined 2,416 people who had experienced an ischemic stroke. In 549 patients, TIAs were experienced prior to the ischemic stroke and in most cases occurred within the preceding seven days: 17 percent occurring on the day of the stroke, 9 percent on the previous day, and 43 percent at some point during the seven days prior to the stroke. â€Å"We have known for some time that TIAs are often a precursor to a major stroke,† said study author Peter M. Rothwell, MD, Ph.D., FRCP, of the Department of Clinical Neurology at Radcliffe Infirmary in Oxford, England. â€Å"What we haven’t been able to determine is how urgently patients must be assessed following a TIA in order to receive the most effective preventive treatment. This study indicates that the timing of a TIA is critical, and the most effective treatments should be initiated within hours of a TIA in order to prevent a major attack.† The American Academy of Neurology, an association of more than 18,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous systems such as stroke, Alzheimers disease, epilepsy, Parkinsons disease, autism, and multiple sclerosis. Common Symptoms of a TIA While similar to those of a stroke, the symptoms of a TIA are temporary, and include: Sudden numbness or weakness of the face, arm, or leg, especially on one side of the body.Sudden confusion or problems understanding.Sudden difficulty speaking.Sudden vision difficulty in one or both eyes.Sudden dizziness, loss of balance or coordination, or difficulty walking.Sudden, severe headache with no apparent cause.

21 Part Time Jobs That Pay More than $20 Per Hour

21 Part Time Jobs That Pay More than $20 Per Hour Need a side gig? Or maybe just a flexible schedule to accommodate your family or other projects, so you can bring in some bacon? You don’t have to settle for a sub-par hourly wage, we promise.   Here are 21- that’s right, 21- part time jobs that pay more than the usual $20 per hour. You can also skip the list, sign up with TheJobNetwork right here to receive the newly posted part time job openings in your location. 1. Freelance Writing: Average ~$26/hrYou can easily make freelance writing a full-time job, or you can take advantage of the good compensation and flexibility and use it as a part-time gig. Start with sites that pay per post if you need a little primary inspiration.2. Landscaping: Average $20+/hrIf you like getting your hands dirty and spending a day doing physical work outside, this can be for you. Start with local one-off gigs on Craigslist, then try to build a word-of-mouth reputation. If you can work specialized machinery, you can make much more- just b e careful to get the necessary licenses and insurance if you start building this into a business.3. Graphic Design: Average $22/hrYou need great computer skills and a keen eye for design, but it’s a great gig if you’ve got what it takes. Make yourself a portfolio of sample work and then make sure you have a website showcasing it, plus any recommendations and rave reviews you’ve won.4. Massage Therapy: Average: $60/hrStrong hands? A desire to help people? Get yourself your Certified Massage Therapist license and start raking in the dough. Work on your own or through health clubs, massage studios, and spas.5. Interpreting/Translating: Average: $23.71/hrIf you’re bi- or multi-lingual, this can be a great way of making some relatively easy money. Work on an on-call basis or by contracting steadier gigs.6. Sign Language Interpreting: Average: $36.50/hrIf you know ASL or another sign language, you can work interpreting in event venues, courtrooms, or classrooms - or even smaller environments like mediations and meetings.7. Tutoring: Average: up to $75/hrBone up on your science and math, specialize in the trickiest of subjects, and you’ll make tons of money. But even vocab and test prep will get you well over $20/hr.8. Test Prep Instruction: Average: $21-$32/hrDepending on the test you’re qualified to teach, this can be a great way to make some extra cash. Work with the SAT, ACT, MCAT, LSAT, GRE or GMAT, and more.9. Personal Shopping: Average: up to $33/hrYou’ll need a decent background in fashion, and a great eye for style, but you’ll make good money and probably have a great time making it.10. Etsy: Depends on what you sell.Are you crafty? Selling your wares on Etsy can be enough to earn a full-time living. Your compensation will depend on what you make, how long it takes you to make what you make, and how much you charge. But the sky’s the limit.11. App Design: Average: $6k/monthAs long as you have the skills and knowledge to develop this kind of software, it can be incredibly lucrative and very flexible work.12. Nannying: Average: $20-$25/hrLove kids? Work daily, weekends, evenings, on-call, you name it- parents have the need and you pocket the cash.13. Personal Chef: Average: $20-$45+/hrStart with pals and friends of friends, and build a reputation by word-of-mouth. Have steady weekly gigs, or cook batches of freezer meals in bulk. If you’re good on the pots and pans, the cold, hard cash is out there for you.14. Catering: Average: $20+/hrIf you don’t mind working evenings and/or weekends, this is a great way to pick up loads of extra money. And good gigs usually open doors for more.15. Bartending: Average: $26/hr (plus tips)You may need certification in your state, and you’ll definitely need skills making cocktails or pouring shots and beer, but no matter what you do, you can make a ton of money if you find the right place and hit on the right schedule. Star t small, rake in the tips.16. Personal Assisting: Average: $25/hrAre you super organized? Don’t mind doing the adult-ing, logistics, and errands for someone else and then getting paid? As long as you’re responsible, discrete, and reliable, this is a great and lucrative gig.17. Serving: TIPSDepending on the volume and the prices of the place, you can make a huge amount of money in tips in relatively few hours. Get your foot in the door and always have this as a fall back side-gig when you need cash fast.18. Yoga Instruction: Average: $24.37-$49+/hrYou’ll need to invest in a Teacher Training series, which takes at least 200 hours and a final assessment, but then you’ll get paid to exercise! You’ll be fitter and richer.19. Fashion Consulting: Average: $50-$500/hrThis is one of those fabled super-high-paying gigs, but if you have a superb eye for fashion and can court the high end clients, it might be for you.20. Dog Walking: Average: $20+/hrFreelance or work with a dog walking company. Get outside, get some exercise, spend time with cute dogs, and†¦ get paid? Start advertising at local pet places- groomers, boarders, vets, pet stores, etc.21. Make-up: Average: $23.50/hrGet brides and celebs and party-goers gussied up for the big event. Have fun while you work. As long as you’re good enough at what you do to keep getting the gigs!

Risk management in Aviva Essay Example | Topics and Well Written Essays - 2000 words

Risk management in Aviva - Essay Example Introduction The current state of this society is an effect of outcome of the long term process. Today, the entire world economy is facing a tremendous growth in every aspect of life. It can be interpreted as an effect of globalisation which can be termed as broadening of the ideas, innovation, relationship and other types of activities among the different countries of the world. Many scholars believe that globalisation is the primary reason behind these. Moreover, they also consider that international trade and business and technological developments are the most importance and crucial effect of globalisation. In fact, the growth of international trade and business and technological advancement are two primary sources of globalisation. In case of international trade, the countries form different parts get opportunities to enter into a new arena of business. In this process, the international traders come into the contact of new experiences like cross cultural diversities, better opp ortunities, and different market exposures etc. Due to effect of globalisation, the nature of trade and business has changed significantly as its importance for inter-dependency has been urged for the development of society. The term, international trade denotes to the commercial transaction between or/among countries that involves transfer of product, wealth, money, services, technology, resources etc. Due to emergence of international trade and business, the world economies have experienced a missive growth. However, with this rapid development, the multinational companies are also being exposed to multiple types of risks. Therefore, in effect, the structure and nature of business and its strategies have been changed to cope up with these risks making the entire process complex (Daniels et al, 2010, p.7). This paper will attempt to analyse the implications of multiple types of risks faced by a multinational organisations. In order to meet this objective, the primary focus of this paper will be on Aviva, a global insurance company. As this company is present in many world economies, it is exposed to a number or risks like political risks, financial risks like interest fluctuations, foreign currency fluctuations, market risks etc. This paper will also include appropriate strategies for diversifying such risks in respect of Aviva’s global insurance business. 2. Brief Description about the Company: Aviva Aviva is one of the most popular global insurance companies in the global financial service market. It is basically an UK-based company and the sixth largest insurance company in the world and the biggest in the UK market (Aviva-a, 2011). The major market for Aviva includes the broad regions like Europe, North America and Asia Pacific market covering more the 28 countries. For its international business management, the company primarily focuses on the three core strategies. Firstly, the company aims to heighten and enhance its focus on geographical segmen ted market. Secondly, it is tries to increase its consumer’s value by offering the best combination of general and life insurance. Thirdly, Aviva is also trying to strengthen its core competencies that have enabled it to be one of the market leaders in global context. The company has gained a high expertise in technical excellence, effective operational, financial discipline and marketing related activities like promotional, distribution etc (Aviva-b, 2011). The company has acquired a large base of consumers in the global market and it service nearly 53.4 million of consumer by offering value-created product with its 45000 employees worldwide. The primary products of Aviva mainly include the life

Business Plan Solutions Essay Example | Topics and Well Written Essays - 500 words

Business Plan Solutions - Essay Example The music retail store can also be funded by informal investors like family, friends, relatives, employees, or colleagues if they are willing to chip-in some of their available money. This possibility of course, is positively related to their support to Rhoda's business venture. More formal sources of equity will be angel investors and venture capitalists. Angel investors are usually affluent individuals who provide capital to small start-up businesses. These individuals often hope for high returns on their investments (Ward, 2000). Rhoda Allegro can also seek equity financing from venture capitalists. Venture capitalists are also individual who supplies capital for the start-up or expansion of a business venture. Like angel investors, venture capitalists are looking for higher returns on their investments than traditional investments. The main difference between angel investors and venture capitalists is that the former is usually equipped with skills in managing a business while the latter is a professional investor. An angel investor is often interested in adding value to the company aside from profiting from his/her investments (Ward, 2000). In summary, Rhoda Allegro's business can be financed by formal and informal sources of financing.

Child cognitive imparment Essay Example | Topics and Well Written Essays - 1000 words

Child cognitive imparment - Essay Example The disease is defined by the center of disease control by a score of 70 and below on the child’s intellectual test capabilities i.e. the IQ test. There are four levels of a child’s cognitive impairments. A child suffering from mild cognitive impairments has an IQ test of 50 to 70 while moderate cognitive impairment has an IQ test of 35 to 55. Severe cognitive impairments with an IQ test of 20 to 40 and profound cognitive impairment where the child has an IQ test of below 20.physical disabilities will usually impact on the way a child controls its body, move and the cognitive and intellectual disabilities will affect the way the way a child thinks and learns. Children develop at different rates. However, there are certain milestones that the healthy child ought to reach by a specific age. The child’s cognitive impairments will affect the developmental milestones of the child (Webster et al., 2006). Cognitive impairments are as a result of a number of factors. Majority of the instances of cognitive impairments are as a result of genetic and chromosomal disorders. Cognitive impairments are also attributed to injuries and illness that occur to the mother during pregnancy or infancy period. Extreme cases of malnutrition to the child, inadequate medical accessibility among the infants, exposure to environmental toxins and chemicals can attribute to cognitive impairments among children. Other causes attributed include genetic diseases, infections on the child such as meningitis, parasitic infections to the child, cerebral malaria, in-utero alcohol and drug exposure during pregnancy, asphyxia, low birth weight, endocrine disorders and head injuries to the children. Most of these causes are preventable. However, it is difficult to prevent these conditions in developing countries. With the many possible causes, it is difficult to define the specific cause of cognitive defect on a child (Ferguson, Hall, Riley, & Moore, 2011). Signs and symptoms

OSHA Considerations for Reducing PELs for Crystalline Silica

OSHA Considerations for Reducing PELs for Crystalline Silica OSHA considerations for reducing PELs for crystalline silica Presented by: Sepideh Sadeghi Introduction Crystalline silica is known as an important constituent in some construction materials like stone, sand, concrete, and granite (1, 2). It comes from different industrial activities such as agriculture, sandblasting, mining, foundry, construction, oil and gas extraction, and hydraulic fracturing (3). Crystalline silica is present in the form of Quartz, Cristobalite and tridymite and all of them are known as a source of exposure in the work places (1, 2). Exposure to crystalline silica can cause silicosis, and a progressive fibrosis of the lungs (2). The National Toxicology Program (NTP) and International Agency for Research on Cancer (IARC) have found two forms of quartz and cristobalite carcinogenic (4, 5). There is a possible mechanism that denotes how this material causes lung disease; when active oxygen species (AOS) is generated by chemicals reactions, it can interact with DNA, proteins, and lipids in macromolecules, then mutation in DNA can initiate the process of cancer or DNA damage (6). The permissible exposure limit (PEL) for respirable crystalline silica (RCS) which is adopted by OSHA is, (RCS): PEL = (10 mg/m3)/ (%silica+2) which restricts both the exposure to RCS and respirable dust (7). The PEL has not updated since the agency was established in 1971. There are many techniques to identify and quantify crystalline silica such as X-ray diffraction methods, Infrared methods, optical and electron microscopy techniques, chemical and thermal analysis. However, some of these techniques have some limitations in their process (8). The purpose of this study is reviewing the OSHA considerations for reducing PELs for crystalline silica. Background Based on the researches done to identify the reason of workers’ illnesses in Vermont granite occurred in 1940 the OSHA proposed the current PEL in 1971(7). The most common symptoms among the workers in Vermont granite were shortness of breath, dry cough, and reduced pulmonary function (9). Then, a recommended exposure limit (REL) of 0.05 mg/m3 for RCS was proposed by NIOSH in 1974 (7, 10) In 1989, NIOSH testified to OSHA that silica should be considered a â€Å"potential occupational carcinogen.† And IARC attested to classify crystalline silica as a carcinogen (7, 11). As a result, the ACGIH accepted to list the silica as an â€Å"A2 Suspected Human carcinogen† In 1999, and, in 2000, adopted a TLV of 50 ÃŽ ¼g/m3 for RCS. In 2006, additional evidences indicated the relation between lung cancer and the inflammation caused by silica, and it led the ACGIH to reduce the TLV to 25ÃŽ ¼g/m3 (9, 12). Results and discussion The detrimental effects of silica on the workers’ health such as lung cancer, kidney diseases and sometimes death necessitated OSHA proposing a new PEL for respirable crystalline silica of 50ÃŽ ¼g/m3 (9). The investigations conducted in the industries showed that workers were at the risk of illnesses and death below the current PELs (9). The following paragraphs address the OSHA considerations for reducing the PEL for crystalline silica. Possibility of Sampling and Analytical Methods The possibility of sampling and analytical methods is between the several limitations that can affect the OSHA decision to reduce the silica PELs. There are some available and accurate personal sampling cyclones like SKC G-3, Higgens-Dowel, Dorr-Oliver, and BGI GK 2.69 which were examined by OSHA for collecting the respirable crystalline silica. According to OSHA, all of these devices are able to collect the silica as low as 25 ÃŽ ¼g/m3 which is needed for the OSHA analytical method of ID-142 (9). Regarding analytical methods to measure silica, two factors of sensitivity and accuracy are investigated by OSHA. The first method that OSHA concludes it has a reasonable sensitivity for measuring the silica was the X-Ray Diffraction (XRD) and Infrared Spectroscopy (IR). However, the poor inter-laboratory results indicated that the mentioned methods are lack of precision. The XRD method of ID-142 presents the precision of  ±23 for the crystalline silica of 50 to 160 ÃŽ ¼g and  ±19 percent for the sampling and analytical error. Therefore, the OSHA could not rely on such colorimetric methods to measure the low amount of silica. Finally, OSHA’s analysis found the laboratories good agreement for the samples in the range of 49-70 ÃŽ ¼g. Therefore, OSHA believes that a PEL of 50ÃŽ ¼g/m3 is more appropriate in the workplaces (9). Possibility of Control Technologies According to possibility of control technologies the OSHA has conducted an analysis for both of general industry sectors and construction industry activities that are potentially affected by the proposed silica standard. 3.2.1. Possibility Findings for the Proposed Permissible Exposure Limit of 50ÃŽ ¼g/m3 According to the results of findings, OSHA assumed that the proposed PEL of 50ÃŽ ¼g/m3 is appropriate for all affected general industries as well as construction activities (9). Thus, OSHA discerned that the PEL of 50ÃŽ ¼g/m3 will be sufficient to maintain in engineering and work practices. And for those few activities within an industry where the proposed PEL is not technologically achievable the workers can achieve the exposure levels at or below the proposed PEL by wearing the protective equipments such as respirators (9). 3.2.2 Feasibility Findings for an Alternative Permissible Exposure Limit of 25ÃŽ ¼g/m3 Regarding to the results of possibility analysis, OSHA concludes that a proposed PEL of 25ÃŽ ¼g/m3 would not be achievable for many industries, and using respiratory protection would have to be required in most operations to achieve compliance. However, there are several industries that have achieved an alternative PEL of 25ÃŽ ¼g/m3 such as asphalt paving products, dental laboratories, mineral processing, and paint and coatings manufacturing in general industry, and drywall finishers and heavy equipment operators in construction industry. In these industries, small amounts of silica containing materials cause to have low concentrations of airborne respirable silica (9). The ferrous foundry industry would not be able to agree with the PEL of 25ÃŽ ¼g/m3 without using the respirators. In the ferrous foundry industry silica is used and recycled to create castings and there is a big amount of silica dust during the process of recycling. Also, the high level silica dust is generated during the shakeout process. The engineering controls determine the exposures below 50ÃŽ ¼g/m3, but the exposure above 25ÃŽ ¼g/m3 still occur. Therefore, the engineering controls in place, reported the exposure range of 13 ÃŽ ¼g/m3 53 ÃŽ ¼g/m3, with many of the reported exposures above 25ÃŽ ¼g/m3(9). The construction industry is similar to the ferrous industry with regarding the generation of dust. Thus, the engineering controls cannot comply to maintain exposures at or below the alternative PEL of 25ÃŽ ¼g/m3. 3.3. Cost of compliance In this section the detailed assessment of the costs to establishments in all affected industry sectors was provided for supporting of the proposed silica rule of reducing worker exposures to silica to an eight-hour time-weighted average (TWA) permissible exposure limit (PEL) of 50ÃŽ ¼g/m3.Table 1 describes the annualized costs of the proposed rule by cost category for general industry, maritime, and construction. The cost is including the engineering controls, respirators, exposure assessment, medical issue, training and regulating areas or access control. Table 1. Annualized Compliance Costs for Employers in General Industry, Maritime, and Construction Affected by OSHA’s Proposed Silica Standard (2009 dollars) (13) Table 1 depicts the total annualized costs of the proposed rule, $132.5 million by general industry, $14.2 million by maritime, and $511.2 million by construction. So, considering the economic feasibility, OSHA standards are economically feasible so long as their costs do not threaten the existence of, or cause massive economic dislocations within, a particular industry or alter the competitive structure of that industry. For example, firms that want to have a profitable line of business may have to increase prices to stay viable. Increases in prices typically result in reduced quantity demanded, but rarely eliminate all demand for the product. This decrease in the total production of goods and services results in smaller output for each establishment within the industry or the closure of some plants within the industry, or a combination of the two, is dependent on the cost and profit structure of individual firms within the industry. So, the economic matter is the controversial subj ect to discuss and there are always some contradictions in companies to accept the cost of new proposed PELs. Conclusion The limitations in the characterization of the precision of the analytical method preclude the Agency from proposing a PEL of 25ÃŽ ¼g/m3. First, the measurement error increases by about 4 to 5 percent for a full-shift sample taken at 25ÃŽ ¼g/m3 compared to one taken at 50ÃŽ ¼g/m3, and the error would be expected to increase further as filter loads approach the limit of detection. Second, for an employer to be virtually certain that an exposure to quartz did not exceed 25 ÃŽ ¼g/m3 as an exposure limit, the exposure would have to be below 21 ÃŽ ¼g/m3 given the error of  ±16 percent calculated from the OSHAs Salt Lake Technical Center (SLTC) study. Based on the information presented in the technological feasibility analysis, the Agency believes that 50 ÃŽ ¼g/m3 is the lowest feasible PEL. An alternative PEL of 25ÃŽ ¼g/m3 would not be feasible because the engineering and work practice controls identified to date will not be sufficient to consistently reduce exposures to levels below 25 ÃŽ ¼g/m3 in most operations most of the time. OSHA believes that an alternative PEL of 25ÃŽ ¼g/m3 would not be feasible for many industries, and that the use of respiratory protection would be necessary in most operations most of the time to achieve compliance. Additionally, the monetary matter is the controversial subject that raises many contradictions in firms to accept the new proposed PELs by OSHA. References 1. Beaudry C., Lavouà © J., Sauvà © J-F., Bà ©gin D., Senhaji Rhazi M., Perrault G., Dion C., Gà ©rin M., (2012), Occupational Exposure to Silica in Construction Workers: A Literature-Based Exposure Database, Journal of Occupational and Environmental Hygiene, 10: 71–77. 2. www.osha.gov/Occupational Health/Projects/Crystalline Silica Exposure.htm 3. Esswein E. J., Breitenstein M., Snawder J., Kiefer, M., Sieber WK., (2013), Occupational Exposures to Respirable Crystalline Silica During Hydraulic Fracturing, Journal of Occupational and Environmental Hygiene, 10: 347-356. 4. International Agency for Research on Cancer (IARC), (2012), A Review of Human Carcinogens. Part C: Arsenic, Metals, Fibres, and Dusts. Lyon, France: IARC. 5. U.S. Department of Health and Human Services (DHHS), Public Health Service (PHS), and the National Toxicology Program (NTP), (2011), Silica, Crystalline (Respirable Size). In Report on Carcinogens. Research Triangle Park, N.C.: DHHS, PHS, NTP, 377–379. 6. Mossman B. T., Jimenez L.A. , Bà ©rubà © K., Quinlan T., Janssen Y.M.W.,( 2011), Possible Mechanisms of Crystalline Silica-Induced Lung Disease, Applied Occupational and Environmental Hygiene, 10:1115-1117. 7. Hewett P., Morey S.Z., Holen B. M., Logan P. W., Olsen G. W., (2012), Cohort Mortality Study of Roofing Granule Mine and Mill Workers. Part I: Estimation of Historical Crystalline Silica Exposures, Journal of Occupational and Environmental Hygiene, 9: 199-210. 8. Miles W. J., (2010), Issues and Controversy: The Measurement of Crystalline Silica; Review Papers on Analytical Methods , American Industrial Hygiene Association Journal, 60:396–402. 9. www.osha.gov/silica/nprm.pdf. 10. National Institute for Occupational Safety and Health (NIOSH), (1974), NIOSH Criteria for a Recommended Standard: Occupational Exposure to Crystalline Silica. HEW (NIOSH) Pub. No.75–120. U.S. Department of Health, Education, and Welfare, NIOSH. 11. International Agency for Research on Cancer (IARC), (1997), Silica, Some Silicates, Coal Dust and Para-aramid Fibrils. IARC Monographs, Vol. 68. Lyon, France: IARC. 12. ACGIH, (2006), Silica, Crystalline: ÃŽ ±-Quartz and Cristobalite. Chemical Substances, 7th Edition Documentation. Cincinnati, Ohio: ACGIH. 13. U.S. Dept. of Labor, OSHA, Directorate of Standards and Guidance, Office of Regulatory Analysis, based on ERG (2007and 2013).

Aristotle, Connectionism, and the Brain :: Philosophy Psychology Papers

Aristotle, Connectionism, and the Brain Can a mass of networked neurons produce moral human agents? I shall argue that it can; a brain can be morally excellent. A connectionist account of how the brain works can explain how a person might be morally excellent in Aristotle's sense of the term. According to connectionism, the brain is a maze of interconnections trained to recognize and respond to patterns of stimulation. According to Aristotle, a morally excellent human is a practically wise person trained in good habits. What an Aristotelian theory of ethics and a connectionist theory of mind have in common is the assumption that the successful mind/brain has the disposition to behave appropriately in appropriate circumstances. According to Aristotle, the good person knows the right end, desires and chooses to pursue it, and recognizes the right means to it. Thus the good person's brain must be able to form certain moral concepts, develop appropriate behavioral dispositions, and learn practical reasoning skills. I shall arg ue that this collection of the brain's cognitive capacities is best accounted for by a connectionist theory of the mind/brain. The human condition is both material and moral; we are brain-controlled bodies with ethical values. My essay seeks to understand the relationship between our brains and our values, between how the brain works and how we make moral decisions. How can the brain be a mind, a conscious person? Recently, some philosophers have argued that human consciousness and cognitive activity, including even our moral cognition and behavior, can best be explained using a connectionist or neural network model of the brain (see Churchland 1995; Dennett 1991 and 1996). (1) Is this right? Can a mass of networked neurons produce moral human agents? I shall argue that it can; a brain can be morally excellent. A connectionist account of how the brain works can explain how a person might be morally excellent in Aristotle's sense of that term. 1. Connectionism The brain receives input and somehow transforms it into output. How does it do it? In part because of the extraordinary technological feats achieved using digital processing computers, the brain has often been interpreted as a symbol manipulator and its cognitive activities as the transformation of symbols according to rules. By contrast, recent successes with parallel distributed processing computers have encouraged a connectionist theory of mind which regards the brain as a pattern recognizer and its cognitive activities as the transformation of neuronal activation patterns; however, these pattern transformations are not rule-governed processes, but straightforwardly causal processes in which networked units (neurons) excite and inhibit each other's activation level.

Analysis of the Effects of Product Cannibalism

PRICING STRATEGY – CANNIBALISM AND NEW PRODUCT DEVELOPMENT – R. A. KERIN M. G. HARVEY J. T. ROTHE 1. My choice I have chosen to work on this topic for these reasons. For many years now, and mostly because of the economic crisis, a lot of « premium  » and mid-range brands have to compete against low-cost ones. In order to do this, some of these companies decided to launch low-cost brands to bring back lost customers.But I have already learned that this strategy can sometimes become a real threat for their premium brands: in fact, companies who do this can think that they bring new customers but unfortunately these customers are coming from their premium brand. Some real life examples are coming to me such as Coca-Cola Company who launched Coca-Cola light and Coca-Cola zero which was successful. How to avoid or reduce the brand cannibalization? What kind of strategy to develop? I hope that this article, even if it's a very old one, can answer these questions. . The su mmary The article starts be giving a definition of the cannibalization effect: we consider 2 different products (A and B) belonging to the same company – cannibalization means that (all other things equal), decreasing the price of product A will bring the sales decreasing of product B. This undesirable effect is occurring when the company, instead of launching a new product, prefer to reformulate one which already exists in an already created market. Authors are putting lights on two main consequences of cannibalistic strategy.The first one is positive, it allows to the company, through the new product, to open a new market, and thus gain market shares. The second seems to be negative, because customers of the first company's product can switch to the second, and it will not bring any additional revenue to the company. But, as authors underline, sometimes it's better for the company to see customers moving from the first product to the second one inside the same portfolio tha n reaching the competitor's product.So, cannibalism strategy can be a good way for the company to kill competitors, but the risk is huge if the new product creates an artificial segmentation which implies artificial needs. The distortion effect of cannibalism is the second main part of the article. Basically, it means that in order to appreciate the profitability of the new product, you must take in account cannibalization of the first one. Authors are talking about  « Pyrrhic Victory  » when one's overestimate the growth of the sales volume and market share due to the new product.Authors provide a solution to avoid this bas effect of cannibalism: the market test. For them it's the best method to know what need(s) the new product will fulfill when it will be launched. This method can help managers to identify (the most early as possible) what amount of the new product should be produced in order to reduce the cannibalization. The question of the  « acceptable  » level of can nibalization is evoked: the two main drivers to compute it are according to the authors the cost structure and market maturity. 3. My opinionOne of the main lessons I learned reading this article is that cannibalism can really be a positive thing for companies. Even if customers of the new product are indeed customers who switched from the previous one, they still not competitor's customers. Far to be a threat, the cannibalism strategy can really be useful and great for companies, especially, as I said in my first part, in time of crisis. Then I think, the article could provide more examples of  « positive  »or  « negative  » cannibalization. The example of Coca-Cola provided at the beginning of this memo is revelatory of the « positive  » cannibalization.In fact, a lot of different soda beverages belong to the Coca-Cola company (such as for instance Fanta, Minute maid or Coca-Cola). In 1983, Coca-Cola company launched Coca-Cola light, which tastes different from the ori ginal Coca-Cola but sugar free ; and then, at the beginning of 2000†², Coca zero was launched which was supposed to have the same taste as Coca-Cola original, and still sugar free. Even if Coca- Cola light lost many customers who switched to Coca zero, they still  « inside  » the same company and not moved to competition.This kind of strategy was learned in our Brand management course that sometimes it consists in creating a similar product can extend the market share of both products. Named the Flanker strategy, the two products are belong not only to the same company but also to the same product category. This strategy has many advantages: it's often almost free to market, as it's very close to the first product and using the same brand, and it was noticed that it's also a good way to promote both products and brands.

Strengthening Federal Clean Air Standards

For Californians, not a day goes by without hearing some remark referring to smog or the quality of the air they breathe. One becomes accustom to shrugging such remarks off without a second thought after a while. Sure the air is getting cleaner, manufactures and people alike seem to be doing all they can do to clean up the air they breathe. Clean air folks are starting to be labeled as reactionaries. As with every organized group there are those among them that deserve such labels, but when it comes down to the air which people have to breathe very day, extra emphasis is a good thing. Federal and local regulations along with public support are responsible for substantial gains in air quality in the last ten years. â€Å"Air quality in Southern California continues to improve, with 1995 registering some of the lowest levels in decades. Yet Southern California still experiences the worst air quality in the nation requiring continued diligence to meet air quality standards† These improvements provide the grounds for continuing the battle for air quality instead of grounds for a pat on the back and job well done. Federal clean air standards should be strengthened. The Environmental Protection Agency (EPA) along with an arsenal of reputable agencies have drafted a plan known as the 1997 Air Quality Management Plan (AQMP) in which detailed summaries regarding current and future air quality measures are brought forward for critics and supporters alike to discern. It is in this plan along with supporting facts regarding beneficial economic gains and support from the medical community that make the case for continuous and stricter air quality standards. The 1997 AQMP sets fourth the guidelines in which the Federal government should set standards for state and local governments along with private agencies to impose and enforce. The focus of the plan comes as a result of new understanding regarding pollutants known as ozone and M10. This new information flows from countless scientific studies. For example, â€Å"Use of the most current air quality information (1995), including special particulate matter data from the PM10 Technical Enhancement Program† . There findings show direct links in ozone and the PM10 pollutants. In chapter three of the plan one can find the scientific data based on base year emission levels dating back to 1987 as they relate to current and future emission levels. Data clearly show's improvement in Southern California's quality of air in the ten year period between 1987 and 1997. The data also provides needed understanding of the major contributors to smog and other ozone depleting pollutants. Overall, total mobile source emissions account for 61 percent of the VOC and 88 percent of the Nox emissions for these two pollutants† The knowledge of this information has been a major factor in the control of these pollutants produced by the vehicles driven by millions everyday weather on the job or just tooling around town with the top down. While the information in this plan requires a good deal of scientific knowledge to understand the general message is clear. Populations are increasing which increases the demands placed on the environment. Without continual improvement regarding air quality there will be massive amounts of ozone depleting emissions created and unchecked in the environment. This plan should be imposed by the Federal government. It provides the method for promising futures not only for the environment but the economy as well. Along with the benefits in improved air quality that will result form the implementation of the 1997 AQMP substantial gains in technology will be achieved in the areas of zero emission vehicles and the development of alternative fuels. On-road motor vehicles which include passenger cars, light duty trucks, medium duty vehicles, heavy duty vehicles, and motorcycles, currently number approximately 10 million in the South Coast Air Basin. † If this seems an alarming number of vehicles of which contribute 61 percent of the VOC and 88 percent of the Nox emissions in the air; you better sit down. â€Å"In 1995 these vehicles traveled more than 300 million miles per day, and by the year 2010, vehicle miles traveled is projected to be about 380 million miles per day† . This is an alarming number of vehicles along with an alarming number of miles to boot. The implementation of the 1997 plan will require the sale of zero-emission vehicles beginning in 2003. This demand places immense pressure on the automotive industry to come up with suitable alternatives for the combustion engine. The technology gains from this industrial effort have already begun to show themselves at car shows throughout the country. All manufactures will benefit from this new technology, from those who produce the batteries that run them to manufacturers of the lightweight materials needed to produce such automobiles. The public reaps immediate gains from this technology such as the cell phone's carried by thousands of people every day in Southern California. Some of the most notable technologies include nickel metal-hydride, lithium-ion, and sodium-nickel chloride. Nickel metal-hydride batteries are responsible for the ability to constantly charge ones cell phone battery without it developing a memory position resulting in limited to no use of the battery at all. Lithium-ion batteries provide extended use of many battery operated items used in every day life such as flash lights, cameras, radios†¦ Honda and Toyota have announced they will introduce pilot fleets of electric vehicles with nickel metal-hydride batteries in 1988 . The examples in technological advancements that result from stricter air quality controls are endless and cannot be fully realized without implementation of the controls described in the 1997 AQMP. As if the available information thus far were not enough to support the EPA's plans for air quality, the medical community has stepped forward to support efforts for cleaner air as well. The proposed plan clearly benefits air quality and the economy through advances in technology. Support from the medical community will convince the stragglers that don't feel air quality and technology will directly benefit themselves. â€Å"Dr. Barry S. Levy, American Public Health Association president and an environmental health physician, called today for the adoption of EPA's proposed regulations to lower levels of particulate (soot) matter and ozone (a chemical that helps cause smog) in the air. This effort will protect children and adults from illness, disability and death, and reduce health care costs by billions of dollars† . Public health is of major concern when it comes to the environment. The air people breath daily is vital to their existence and the quality of that air is one of the major factors to their quality of life. According to DR. Levy, â€Å"The proposed EPA standard are based on well-designed scientific studies that link adverse health effect to the fine particulate matter and ozone† . The American Public Health Association (APA) is considered on of the oldest and largest organizations devoted to public health. The APA credits itself with some of the top professionals in the field of public health. They have conducted more studies and published more information regarding public health than any other organization of its kind in the world so when they support the EPA's findings for stricter air quality control measures they speak for a vast majority of health professionals. Common sense requires one to feel a sense of dread at the possibility of death as a result of poor air quality. The EPA has built a sound case for enacting stricter air qualities and they have a great plan for its enactment. It is clearer now that the adoption of the 1997 AQMP has far reaching benefits for all. Scientifically sound evidence points to the reality of cleaner air from the plans enactment. Increases in technology will create economic growth and business opportunity. And finally health risks resulting from poor air quality can be substantially reduced for both children and adults. The 1997 AQMP also provides measures for meeting the standards proposed in its regulations. Through, â€Å"Intercredit Trading Program, Air Quality Investment Program and Promotion of Catalyst-Surface Coating Technology Programs for Air Conditioning Units. These measures are designed to enhance compliance flexibility, to facilitate the implementation of the command and control measures† . The command and control measures of the plan are simply implementation and enforcement policies which incorporate assistance and rewards for complying to regulations. Most of these programs are already successfully being operated at the present time. There is also an Air Quality Assistance Fund which has been enacted to help small businesses comply with stricter emission regulations. The plan provides a â€Å"loan guarantee for up to 90 percent of the loan amount, ranging from a minimum of $15,000 to a maximum of $250,000† . Money can be used for retrofitting operations to the point of complying with any portion of the AQMP. A study conducted buy Dr. Steven Meyer, director of the Massachusetts Institute of Technology's Project on Environmental Politics and Policy says, â€Å"‘Job growth–not job loss– is associated with stronger environmental policies. The 10 states with the strongest environmental policies appear to have experienced annual employment growth rates almost . 6 percent higher than those of the 10 states with the weakest environmental policies'†. Opponents of Federal regulations often rely on job scare tactics to kill a useful initiative such as the one proposed by the EPA but the facts are, jobs are created when improvements in technology are made. The plan provides a complete package from reasons for change through benefits of such changes right down to the actual implementation of its policy's. It provides areas of assistance for those who have trouble with compliance and places adequate emphasis on continued improvement in all areas regarding air quality. With regard to the health of the planet and the there is little reason remaining for the Federal government not to enforce stricter air quality measures.

Love and Relationship

Love and Relationship The word ‘love’ is observed to have distinct meanings in various settings and contexts. Different people from various cultural settings would tend to have different perceptions about love. Generally, love refers to some kind of inexplicable feeling which is felt by people towards others, probably those of the opposite sex. Relationship on the other hand would refer to the condition of people being connected or associated with each other.Advertising We will write a custom essay sample on Love and Relationship specifically for you for only $16.05 $11/page Learn More We have all experienced love at one moment of life, but it is as though there is still much we don’t know about love itself. Humans have always asked inexplicable questions about love such as, â€Å"Why do we fall in love?† or â€Å"What makes us love others?† We may not necessarily have perfect answers for all the questions regarding love but there is no doubt tha t we have been closer to the right answers for most of these questions through the perception of psychologists. For instance, according to love psychologists, the reason as to why we fall in love will depend on our minds. The way our minds perceive love is what comes out to us as love. Sometimes, these perceptions may match with the perceptions of another person and in that case love is certain to be realized. Different groups of people have different views about love. Some communities would see it as something that would be contained in the eyes while others just associate it with blood thus the observations ‘love is in the eyes of the beholder’ and ‘blood is thicker than water’ respectively. However, some aspects in life have come up to disqualify these perceptions, making people to search for other alternative explanations. For instance, let us consider the situation of blind people. Does their incapability to see hinder them from loving? More importantl y, if love was really contained in the blood, will there be any cases concerning lost identities in life as we can see today? Having asked ourselves these questions, it would be easy for us to appreciate the psychological view of love that is determined by our minds as the perfect answer to most of the questions we frequently ask ourselves regarding love. The issue of love and what makes people fall in love has been a subject of debate all over the world for a very long time. There may never be false love as some thinkers would observe, but we are all informed of the many uncertainties associated with love nowadays. Think of someone who is strolling down the street without any specific focus or intention then suddenly, he bumps on a lady and it happens they fall in love at the first sight. How can this situation be explained? There is no other perfect manner we can explain this but through the ‘idea of the mind.’Advertising Looking for essay on psychology? Let's see if we can help you! Get your first paper with 15% OFF Learn More What had just happened between the two people would depend on their brains. Single people; ones who are not in any relationship will always be in hunt for love and if someone fitting their criteria crosses their path, they will definitely be attracted to them and these feelings would trigger love instantly. The person in this example fell in love with the lady she met on the street owing to the opportunistic perceptions of his mind that he was single and he needed a lover. This is just what happens to many people in this world as far as love is concerned. As it would be observed, most people would appear to be crazy in love at the beginning of their relationship. This however is likely to change over the time and that fire would fade away as they continue seeing each other. They can even start having feelings of hate against each other. This is another stand which can be used to justify the hypothe sis in this argument. Most of the times, humans are misguided by their minds to make instant choices about love, instead of taking their time to think of the possible outcomes which are likely to arise later. This way, they end up making the wrong choices in what can be termed as ‘rushed love.’ This is a misunderstood situation that would be characterized by arguments and hate against each other come in the future. To avoid such situations, psychologists have observed a number of factors for people to consider before thinking of falling in love. First of all, we should try to establish a checklist about the things we expect to see in our future lovers and some of the aspects which can apply in the checklist might include behavior, appearance, and education. A checklist is more likely to guide us to the right people thus sparing us future disappointments in relationships. Through the observations of this topic, we get to learn the benefits of psychology in helping us com e into terms with some behaviors and processes of life. Through psychology, we can gain practical benefits regarding various aspects of life. Psychology is always certain to offer satisfying answers to most of the questions we may frequently ask ourselves about many things facing us in our daily lives. For instance, in the above case concerning love psychology would provide the right answers and the perfect guideline on how to go about it without regrets. This would help people make the right decisions thus avoiding future disappointments. In this case, we should see the capability of psychology in giving us the perfect guideline about sensitive issues of life.Advertising We will write a custom essay sample on Love and Relationship specifically for you for only $16.05 $11/page Learn More

6 Disappeared LinkedIn® Partner Applications and What to Do About Them †Part II Amazon Reading List

6 Disappeared LinkedIn ® Partner Applications and What to Do About Them – Part II Amazon Reading List Are you an avid reader? It used to be that you could share your passion easily on LinkedIn with the Amazon Reading List application. With the disappearance of LinkedIn partner applications came the elimination of this option. Amazon Reading List was a valuable way to let people know what type of professional development you were engaged in, as well as to round yourself out as a human being (read any good novels lately?) Many people are wondering how to include a reading list on LinkedIn now that the old method has vanished. I was fortunate to have one of my fellow LinkedIn authors, Patrick Gallagher, (LinkedIn Secrets Revealed) do some research on this topic. He wrote to Amazon and received the following email: Thank you for using Reading List by Amazon and for your patience as we’ve worked to make your book information available after LinkedIn deprecated their application program. Your Reading List information has been preserved and is available for import on Shelfari.com. Shelfari is an Amazon-owned site that helps you keep track of the books you’ve read and are reading, discover new books and interact with other readers. Go to https://www.shelfari.com/addbooks. You can sign in to Shelfari using your Amazon account (or your existing Shelfari account). If you’re already a member, click â€Å"Import Books† from the Your Shelf drop-down on the home page. Click the â€Å"Import Books† from the Your Shelf drop down or go directly to: https://www.shelfari.com/addbooks and you will be guided through importing your books and reviews to your Shelfari bookshelf. I followed these instructions and the process was pretty straightforward. I went to the link provided, www.shelfari.com/addbooks, and created an account. I then entered the same link again and was brought to this screen: When I clicked on IMPORT next to Import Your LinkedIn Reading List, all I had to do was provide my LinkedIn password and my reading list showed up in Shelfari! I then clicked on the Account Settings tab and customized my Shelfari link: Now that I have a link, I can add it to my LinkedIn Profile using the new platform. Here’s how to add a link in the new LinkedIn: In the Summary section, click on the blue box with a + sign in the corner. You will be brought to a box where you can paste a link: After you paste the link, you can provide a title and description: Unfortunately, there’s a small glitch. When I clicked on the link, the following screen appeared: I had to click on Read Original to get to the actual Shelfari list, which looks like this: In Shelfari, you can add books you have read or that you are reading, rate them and review them. I won’t give a tutorial on the website since I think you can figure it out by poking around! If this all seems too complicated, you can do as Patrick Gallagher did and add the Projects section to your profile. You can then create a â€Å"project† called â€Å"Amazon Kindle Book Reading List† or something similar, and list your books there. Here’s Patrick’s list: Another option would be to create a document with your list of books and upload it to Box.net. You can then add a link to the Box.net file on your LinkedIn profile. I will cover more about Box.net in my next entry of this series. Stay tuned, and happy reading! Want to read How to Write a KILLER LinkedIn Profile on Kindle? Curious about Patricks book? Check it out here: Category:Archived ArticlesBy Brenda BernsteinJanuary 28, 2013 2 Comments Laveda says: June 24, 2014 at 7:27 am The nerd in me was thoroughly excited to read this article because the Amazon Reading List was one of my favorite LinkedIn apps and I was a little dishearten to see it wasnt there anymore. Thank you for finding other options to provide a reading list. Ill definitely add one later this week. In all honesty, I enjoyed viewing my LinkedIn network readings on my news feed. That I will always miss. Laveda Log in to Reply The Essay Expert says: June 24, 2014 at 8:16 am Thanks for your comment Laveda. With LinkedIns new Publishing platform, you should once again have easy access to educational content from your network! Log in to Reply